Constipation 3. I can already say this is my alternative to DXM. memantine Hydrochloride Tablet is contraindicated in patients with known hypersensitivity to memantine hydrochloride or to any excipients used in the formulation. Memantine hydrochloride extended-release capsules are supplied for oral administration as 7 mg, 14 mg, 21 mg, and 28 mg capsules. Multiple trials have found that memantine can attenuate some of the side-effects of cocaine abuse. The self awareness memantine provides is one of the key factors why I enjoy it over other dissos, you can very easily gauge how much it is effecting you and take precautions so your situation is rarely ever precarious. I bought memantine awhile back and took 15mg twice a day for 3 days. Whether its a question, picture, or information. Overview; Side Effects; Dosage * DPH as a medicine. http://scs-assets-cdn.vice.com/int/v18n2/htdocs/interview-with-ketamine-chemist-704/drug-structures.gif. Keiski, in New Therapeutics for Traumatic Brain Injury, 2017. Thanks for your information! Memantine (0, 15, and 30 mg) was administered 4 h before alcohol (1.5 g/l body water), which was given in four divided doses every 20 min. Then memantine is pulled into the channel to its binding site. Memantine hydrochloride 20 mg film-coated tablets are Please also state how often you are dosing and with what dosages, and please describe roughly what you believe your tolerance to be. Contraindications. (note: I'm a ~70kg male). Find more subreddits like r/MemantineHCl -- A sub for discussing all uses of Memantine, from therapeutic to recreational. For more information on Memantine read: Memantine Wikipedia It has a role as a dopaminergic agent, an antiparkinson drug, a NMDA receptor antagonist, a neuroprotective agent and an antidepressant. Memantine, or known as Memantine HcL, is an uncompetitive NMDA receptor antagonist, and thus relies on glutamate’s activation of the NMDA receptor to take effect. Memantine is used to manage moderate to severe Alzheimer's dementia Label.. A more recent systemic review and meta-analysis 6 indicates that memantine is beneficial as a first line drug for the treatment of Alzheimer's dementia. I consider trying to get high off memantine to be about as good an idea as trying to trip off benadryl or nutmeg. Keep the liquid medicine bottle tightly closed with the cap provided. When you first start taking this medication, you will usually take it once daily. 20mg per mL in a 30mL bottle. I then took 50mg in the morning followed by 50mg more in the afternoon. So I never do anything stupid because I don't realize I'm fucked up. If experienced, these tend to have a Less Severe expression 1. <insert manic paragraph describing our speedy community in vivid detail, describing at great length the community, the rules, the daily goings-on etc., hopefully with many run-on sentences and a general lack of focus or point> The memantine dosage will differ based on the use case. Granted, it may not be for everyone, but to say it's an objectively 'awful' recreational drug is incorrect. A subreddit for the sharing and discussion of research chemical vendors. Colors were much more defined, and everything became surreal almost as if it were placed there with some higher meaning, like the "doll-house" effect, maybe I should call it the "M-house" effect, lol. Also consider supporting Psychonaut Wiki & Erowid as they provide invaluable information for free to anyone who needs it. Just wanted to put some stuff out there as there's not a whole helluva lot of reading material on memantine. It didn't really hurt but I definitely bruised my bone or something because for the next few days I was hurting pretty bad. This drug will pretty much wreck your dissociative tolerance, so don't plan on getting much fun out of any other dissos for weeks or maybe months after a recreational dose of memantine. The things that do work/produce an effect will eventually have a deleterious effect on the mind. We are a migrant community mostly from the previous sub NovelDissos. Does Memantine HCL Interact with other Medications? It is taken by mouth. Sourcing drugs is NOT allowed here! Definitely has similar numbing qualities as other dissociatives. Overall, this is a very long lasting drug, but even at high doses I felt l still felt pretty in control. EC Number 255-219-6. Strictly no sourcing. For the discussion of recreational pharmacology. A place to discuss Salvia divinorum, a psychoactive plant traditionally used by Mazatec shamans. I wasn't noticing much effects(I bought it basically for recreational use but read that even taking this much could be intoxicating after a couple of days). As it stands the dosing range on Memantine's Psychonaut Wiki page was submitted by a single user with unknown sources. For those who want to use memantine for … These medications may interact and cause very harmful effects. Memantine hydrochloride was evaluated in eight double-blind placebo-controlled trials involving a total of 1862 dementia (Alzheimer's disease, vascular dementia) patients (940 patients treated with memantine hydrochloride and 922 patients treated with placebo) for a treatment period up to 28 weeks. I weigh 120lbs-125lbs. I'm no stranger to dissociatives so it wouldn't have been too bad if I ended up getting a little inebriated during this process. At the peak of the dissociation, I find it difficult to communicate with people (mainly via text). This means that for memantine to bind, the neuron has to depolarize, and open to clear the magnesium block. This is where you come in, we would like you to leave a comment here describing what you would consider a Threshold, Light, Common, Strong & Heavy dose. But at the same time, I"m 100% consciously aware of the fact that my cognitive abilities are impaired. Memantine HCl occurs as a fine white to off-white powder and is soluble in water. Pictures of drug and paraphernalia collections, and large amounts of drugs. I read that as mermantine and got very excited. Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. I think it's interesting that you, and like others have reported, have said that you're fully aware of the impairment memantine brings, although it's not a turn off for you. It's difficult to tell if you've reached the Mem-Hole or not, because in my experience, to really achieve it you have to find a very calm place, allow your mind to drift and more or less meditate for a lack of a better term, until you've disconnected from reality. Welcome to r/DXM - the official subreddit for discussion of the powerful dissociative cough suppressant - Dextromethorphan! Very pleasant dreams. A friend and I went exploring as I just bought this house and it's pretty much in the middle of nowhere. Ill continue later.... New comments cannot be posted and votes cannot be cast, More posts from the MemantineHCl community. memantine Hydrochloride 10 mg tablet: round, film-coated tablets are gray, with the strength (M10) debossed on one side and X on the other. M.A. This includes: URLs, markets, PMs, etc. Confused 2. A threshold dose is the minimum dose required to feel the recreational effects, with each range increasing in effects. Memantine hydrochloride 10 mg Film-Coated Tablets Memantine hydrochloride 20 mg Film-Coated Tablets Memantine hydrochloride Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Definitely a much clearer headed high than other dissociatives, lacking most of the traditional body high in exchange for a more cerebral oddity type feel. Ask questions about drugs that you already typed into google, After the slow and painful death of MXE in 2015, researchers of the research chemical community have been searching for a replacement. I ended up getting too confident and falling down this hill and hitting my leg on a piece of concrete. The only positive is it's pretty good at getting rid of anxiety, your brain isn't working enough to be anxious. Modafinil (Provigil, Modalert) and related compounds. I would suggest maybe extending the common up to 120 or 130, and upping the strong to 200mg, with heaving being anything 200 and above. I had pretty intense close eyed visuals for most of the night, not really knowing if I slept at all when I got of bed the next day. Once your dose increases to more than 5 milligrams per day, take this medication twice daily or as direc… Memantine Dosage. Your doctor will need to check your progress while you are using memantine. A place to discuss obscure drugs. A sub for discussing all uses of Memantine, from therapeutic to recreational. A psychonaut is a person who experiences intentionally induced altered states of consciousness and claims to use the experience to investigate his or her mind, and possibly address spiritual questions, through direct experience. r/depressionregimens is a sub for redditors with depression and anxiety who are looking to be part of a constructive community dedicated towards improvement, with a focus on safe and researched substances. All I can say is its a very clean dissociative. Strictly no sourcing. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. And it lasts fucking forever, so you take 100mg and you don't like it, prepare to feel that way for three days and likely have a car accident and some serious amnesia. I've also tabulated this data for easier reading: I was gonna post my report haha thank you for beating me to it. I was pretty dissociated but it lacked the euphoria and pretty much any 'fun' aspect of a recreational dissociative. I was able to mix 50 mg of memantine hydrochloride into 1 ml of distilled water only after applying light heat to increase solubility. These are currently the few reliable reports of recreational Memantine use: Reported Dose: 150mgDescribed Experience: Heavy (Hole-like experience)Reported Tolerance: unknown, some dissociative experienceSource: https://erowid.org/experiences/exp.php?ID=109838, Reported Dose: 150mgDescribed Experience: Heavy (Hole-like experience)Reported Tolerance: Experienced userSource: https://erowid.org/experiences/exp.php?ID=109789, Reported Dose: 20mg (In conjunction with 600mg of Gabapentin)Described Experience: Threshold-LightReported Tolerance: Zero experience with Memantine, some experience with other dissociativesSource: https://erowid.org/experiences/exp.php?ID=105696, Reported Dose: 100mgDescribed Experience: Common-StrongReported Tolerance: some dissociative experienceSource: https://erowid.org/experiences/exp.php?ID=100894, Reported Dose: 100mgDescribed Experience: CommonReported Tolerance: unknown, user reports previous use of DXMSource: https://drugs-forum.com/threads/100mg-memantine.248883/, Reported Dose: 4x doses ranging between 50-100mg (200-400mg total)Described Experience: HeavyReported Tolerance: unknownNote: recommends 50-100mg for common useSource: https://erowid.org/experiences/exp.php?ID=32398, Reported Dose: 80-100mgDescribed Experience: Light-CommonReported Tolerance: unknownSource: https://drugs-forum.com/threads/memantine-experience.286366/, (From the same thread as above)Reported Dose:50mg (1st Day), 90mg (2nd Day), 160mg (3rd Day)Described Experience:Day 1: (Light), Day 2: (Light-Common), Day 3: (Strong)Reported Tolerance: UnknownSource: https://drugs-forum.com/threads/memantine-experience.286366/, Reported Dose: 280mgDescribed Experience: Strong-HeavyReported Tolerance: unknownSource:https://drugs-forum.com/threads/memantine-experience-high-dose.296411/. My sense of balance and coordination were fairly thrown off. This has taken me several hours before and by the time I've reached the depths of the memanverse I've forgotten I was even in my bed before (or wherever), leaving me in great voids and dark, space-filled structures, with no thoughts about the outside world. But it wasn't very fun. It is a long acting NMDA receptor antagonist that binds to an open channel binding site. YOU WILL BE BANNED FOR ASKING OR PROVIDING DRUG OR PARAPHERNALIA SOURCES, whether illegal or legal. Consequently, there is a large pool of high-quality evidence that supports memantine’s use in moderate-to-severe cases of Alzheimer’s disease (AD). 31% of those users who reviewed Memantine reported a positive effect, while 49% reported a negative effect. ), and general discussions on different categories of supplementation. Molecular Weight 215.76 . You may need to read it again. what should I take? A friend of mine liked it so I just gave it to him. Diarrhea 5. So I've tried memantine at recreational doses about 3 different times now, this is what I have to report. I got a little bit of double vision as this dose, with a slight amount of other dissociatives visuals, mainly scenery slicing. Head Pain But it is very pleasant sleep. If one does not mind waiting a few hours for the effects to be felt, and due to the pain involved with intramuscular injection, I believe … I've taken memantine at 20mg/day for ~3 months, effectively, and recreationally/experimentally, once at 50 mg-common dose (effects: gnawing hunger/empty feeling in stomach, dizziness/"whoosh" feeling when moving my head, increased interest in everything, less/no fidgeting/increased concentration). Hi, it seems like this is a subreddit for the recreational use of Memantine (sorry if I'm mistaken), which makes me a bit worried that it was prescribed for my father (Ebixa 10 mg, pill a day for 1 month) as a treatment for his sudden memory/cognitive issues due to Small Vessel Disease. Memantine, or 3,5-dimethyladamantan-1-amine, is a man-made molecule classified as a substituted adamantane derivative. For me, nothing works. I'm also a woman of normal height and weight (5'6"; 125 lbs). Trying 50mg Memantine tonight. Please help by taking a moment and letting us know how you use memantine! This had me feeling pretty nice. This is a subreddit about DPH. Memantine may be useful for treating substance abuse and dependence. But it is an absolutely awful recreational drug- taking, without tolerance, any amount, but particularly an amount above 30mg just makes you feel braindead and generally shitty. It's a lot of the not so great effects ketamine has with none of the good effects. Make sure you follow the RULES. I'm pretty experienced with dissociatives, so it had been a while since I've felt something I could compare to a true-robo walk, but this seemed to fit the bill. It's mainly about the recreational use of DPH, but posts about using DPH as it was intended are welcome, too. From experience the tolerance issues come heavily into play when dosing more regularly or for a longer period than this. Serious Interactions. Also you mentioned this 'doll-house' type effect, I've been coining the term 'Memanverse' to describe what I think you are saying. Get your prescription refilled before you run out of medicine completely. Use memantine regularly to get the most benefit. A dedicated subreddit for the discussion of synthetic psychoactive research chemicals. A sub for discussing all uses of Memantine, from therapeutic to recreational. It's a looooong trip. It comes in three forms: immediate-release tablet, oral solution, and extended-release capsule. Do some research, ask a question, get an answer. Posted by 2 days ago. Cough 4. User Reviews for Memantine to treat Alzheimer's Disease. This extends into what is the Memantine equivalent of a K-hole, which when compared to Ketamine is much more clear-headed. Memantine: Formulations, Dosages, Contraindications, and Side Effects. Discussion of all things related to the narcotics known as opiates, from harm-reduction to pharmacology. Feel free to share helpful hints, tips, and news about kratom. I personally have replaced all other dissociative use (including a previous Ketamine addiction, and regular DXM use) with Memantine. That's basically all I have. Hunting ethnobotanicles is also encouraged. NAMENDA oral solution contains memantine hydrochloride in a strength equivalent to 2 mg of memantine hydrochloride in each mL. This includes new research, potential supplement choices (ie. You can read more specifically which term describes what range of effects here. Memantine is substituted with a methyl carbon at both R3 and R5; it contains an amine substitution at R1. Both the research  and anecdotal reports  recount as much. It was when I found a source or Memantine powder that I started experimenting with more recreational doses. Warnings and Precautions Common side effects … I didn't feel much with the first dose, possibly due to an increased tolerance since it wasn't super long since the last time I took it, (which I do not recommend... apparently taking it to often can fux with neuroplasticity levels), but a few hours after the second dose things got pretty warbly. Every bit helps, even if you didn't enjoy Memantine, it's important for people to know what they can before deciding to try the drug themselves. Confidence issues are because I feel that I haven't accomplished anything in my life besides a highschool diploma. The 3rd time I took 150mg, followed by another 150mg about 4 hours later. Check out the /del/ discord: https://discord.gg/G3yV8Te, Tianeptine (Stablon) Discussion & Experiences. Welcome to the place for discussion of kratom. Once you finally feel the urge to go curl up in your bed under your blankets, don't be surprised if you sleep for 16 hours straight. The supplements subreddit aims to discuss and share topics related to nutritional supplementation. Plants, cactus, mushrooms, herbs, and others are welcome. I have a lot of experience. And personally, I've never had a bad time while under the influence. * Chemistry-related DPH stuff This is yet another reason why I love this substance, I don't think I've had such a clean and clear headed disconnection from reality without feeling heavily impaired at the same time. on the real, a place for humans who prefer to go fast (in whatever way they like) to come together, commune, communicate, share stories of our lives, ask questions, share knowledge (always in the interest of harm reduction), make friends, and revel in the wonders of life. 348. Memantine hydrochloride oral solution is a prescription medicine used for the treatment of moderate to severe dementia in people with Alzheimer's disease. Follow your doctor's instructions carefully. Memantine hydrochloride 10 mg film-coated tablets are pale yellow to yellow, oval shaped film-coated tablets with breaking line and engravings 1 0 on one side and R R on the other side. 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